2381/33380 A. Poma A. Poma Antonio Guerreiro Antonio Guerreiro Sarah Caygill Sarah Caygill Ewa Moczko Ewa Moczko Sergey Piletsky Sergey Piletsky Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water University of Leicester 2015 IR content 2015-10-26 13:09:04 Journal contribution https://figshare.le.ac.uk/articles/journal_contribution/Automatic_reactor_for_solid-phase_synthesis_of_molecularly_imprinted_polymeric_nanoparticles_MIP_NPs_in_water/10176674 We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, “ready for use” MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.