2381/33758
G. F. Jay
G. F.
Jay
Enantoioselective reactions of some optically active phosphines.
University of Leicester
2015
IR content
2015-11-19 08:45:54
Thesis
https://figshare.le.ac.uk/articles/thesis/Enantoioselective_reactions_of_some_optically_active_phosphines_/10188542
The enantioselective chlorination of alcohols by the menthyldipheny1-phosphine/carbon tetrachloride reagent previously reported in the literature was investigated and quantified. Further examples were found. A new enantioselective reaction of menthyldipheny1phosphine/carbon tetrachloride was discovered. This was the synthesis of aziridines by ring closure of ? amino alcohols. Other optically active phosphines in conjunction with carbon tetrachloride were found to react in a similar manner to menthy1dipheny1phosphine/carbon tetrachloride with a variety of ? amino alcohols. Menthy1dipheny1phosphine was found to react enantioselectively with a ? amino alcohol in the presence of chlorine.