2381/12382877.v1 Thomas Yates Thomas Yates Cameron Razieh Cameron Razieh Francesco Zaccardi Francesco Zaccardi Melanie J Davies Melanie J Davies Kamlesh Khunti Kamlesh Khunti Obesity and risk of COVID-19: analysis of UK Biobank University of Leicester 2020 Uncategorised value 2020-05-29 09:21:25 Journal contribution https://figshare.le.ac.uk/articles/journal_contribution/Obesity_and_risk_of_COVID-19_analysis_of_UK_Biobank/12382877 [First paragraph] Whilst emerging evidence has suggested that those with cardiometabolic diseases are at higher risk of severe COVID-19 and<p></p><p>resulting complications, less is known about the relative importance of related lifestyle factors. Obesity in particular is associated with</p><p>impaired pulmonary function, a suppressed immune system and has been identified as a risk factor in previous infectious outbreaks.</p><p>Obesity also appears to be prevalent in subjects with COVID-19. However, as recently highlighted, there is a lack of information</p><p>regarding the nature of association between body mass index (BMI) and COVID-19. In order to inform this area, we investigated the association between obesity and laboratory confirmed COVID-19 within UK Biobank (application number 36371). Our hypothesis was that BMI and waist circumference would be independently associated with COVID19.</p>