Advances in exercise therapy in pre-dialysis CKD, hemodialysis, peritoneal dialysis and kidney transplantation
Thomas Wilkinson
Mara McAdams-Demarco
Paul Bennett
K Wilund
2381/12527096.v1
https://figshare.le.ac.uk/articles/journal_contribution/Advances_in_exercise_therapy_in_pre-dialysis_CKD_hemodialysis_peritoneal_dialysis_and_kidney_transplantation/12527096
<p><b>Purpose of review</b></p>
<p>Chronic kidney disease
(CKD) is characterized by poor levels of physical activity which contribute to
increased morbidity across the disease trajectory. The short nature, small
samples, and poor methodology across most studies have failed to translate the
role of exercise in CKD into its adoption as a frontline adjunct therapeutic
option. This review focuses on recent advances surrounding the benefits of
exercise interventions across the CKD spectrum. </p>
<p> </p>
<p><b>Recent findings</b></p>
<p>Key recent advances in
exercise studies have focused on the efficacy of novel intervention strategies
across the CKD spectrum. These include high-intensity interval training, virtual
reality gaming, intradialytic yoga, electrical stimulation of muscles, blood
flow restriction training, and protocols combining exercise with nutritional
supplementation. Research is also beginning to explore the role of
prehabilitation for patients prior to dialysis and kidney transplantation.</p>
<p> </p>
<p><b>Summary</b></p>
Studies continue to
demonstrate wide-ranging benefits of exercise across CKD; however,
implementation of exercise remains scarce.
Future research needs include evaluating the efficacy of larger and/or
more comprehensive interventions on clinically important outcomes. It is hoped with increasing global evidence, high-quality
clinical studies, and sustained clinician and patient engagement, exercise
programs will become better prioritized in the nephrology field.
2020-06-25 13:00:18
Exercise
Physical activity
Intradialytic exercise
Physical function
Chronic kidney disease
Dialysis