2381/12593612.v1
David Koeckerling
David
Koeckerling
Joseph Barker
Joseph
Barker
Nadeesha L Mudalige
Nadeesha L
Mudalige
Oluwatobiloba Oyefeso
Oluwatobiloba
Oyefeso
Daniel Pan
Daniel
Pan
Manish Pareek
Manish
Pareek
Jonathan P Thompson
Jonathan P
Thompson
G Andre Ng
G Andre
Ng
Awake prone positioning in COVID-19.
University of Leicester
2020
critical care
respiratory infection
viral infection
2020-07-06 15:02:22
Journal contribution
https://figshare.le.ac.uk/articles/journal_contribution/Awake_prone_positioning_in_COVID-19_/12593612
In the absence of effective targeted therapies for COVID-19, optimisation of supportive care is essential. Lung injury with features of acute respiratory distress syndrome (ARDS) appears to be the principal characteristic of severe acute respiratory syndrome coronavirus 2 infection.<a href="https://thorax.bmj.com/content/early/2020/06/15/thoraxjnl-2020-215133#ref-1">1</a> Recent guidance by the UK Intensive Care Society (ICS) advocates awake prone positioning to become standard of care for suspected or confirmed COVID-19, in patients requiring an FiO2 ≥28%0.<a href="https://thorax.bmj.com/content/early/2020/06/15/thoraxjnl-2020-215133#ref-2">2</a> These recommendations are extrapolated from physiological principles and clinical evidence obtained in a distinct study population—patients with severe ARDS undergoing invasive mechanical ventilation (IMV). [Opening paragraph]