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Connecting the dots in Huntington's disease with protein interaction networks

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journal contribution
posted on 2012-10-24, 09:04 authored by Flaviano Giorgini, Paul J. Muchowski
Analysis of protein-protein interaction networks is becoming important for inferring the function of uncharacterized proteins. A recent study using this approach has identified new proteins and interactions that might be involved in the pathogenesis of the neurodegenerative disorder Huntington's disease, including a GTPase-activating protein that co-localizes with protein aggregates in Huntington's disease patients.

History

Citation

Genome Biology, 2005, 6 (3), pp. 210-210

Version

  • VoR (Version of Record)

Published in

Genome Biology

Publisher

BioMed Central Ltd

issn

1465-6906

eissn

1465-6914

Copyright date

2005

Available date

2012-10-24

Publisher version

http://genomebiology.com/2005/6/3/210

Language

eng