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Obesity and risk of COVID-19: analysis of UK Biobank

journal contribution
posted on 2020-05-29, 09:21 authored by Thomas Yates, Cameron Razieh, Francesco Zaccardi, Melanie J Davies, Kamlesh Khunti
[First paragraph] Whilst emerging evidence has suggested that those with cardiometabolic diseases are at higher risk of severe COVID-19 and

resulting complications, less is known about the relative importance of related lifestyle factors. Obesity in particular is associated with

impaired pulmonary function, a suppressed immune system and has been identified as a risk factor in previous infectious outbreaks.

Obesity also appears to be prevalent in subjects with COVID-19. However, as recently highlighted, there is a lack of information

regarding the nature of association between body mass index (BMI) and COVID-19. In order to inform this area, we investigated the association between obesity and laboratory confirmed COVID-19 within UK Biobank (application number 36371). Our hypothesis was that BMI and waist circumference would be independently associated with COVID19.

Funding

This work was supported by the NIHR Leicester Biomedical Research Centre and NIHR Applied Research Centre East Midlands. Data was analysed using UK Biobank application number 36371

History

Citation

Please cite this article as: Yates T, Razieh C, Zaccardi F, Davies MJ, Khunti K, Obesity and risk of COVID-19: analysis of UK Biobank, Primary Care Diabetes (2020), doi: https://doi.org/10.1016/j.pcd.2020.05.011

Version

  • AM (Accepted Manuscript)

Published in

Primary Care Diabetes

Publisher

Elsevier BV

issn

1751-9918

Copyright date

2020

Spatial coverage

UK

Language

en

Publisher version

TBA

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