University of Leicester
Browse
The loss in expectation of life after colon cancer: a population-based study..pdf (598.67 kB)

The loss in expectation of life after colon cancer: a population-based study

Download (598.67 kB)
journal contribution
posted on 2016-01-28, 11:09 authored by T. M. Andersson, P. W. Dickman, S. Eloranta, A. Sjövall, M. Lambe, Paul Christopher Lambert
BACKGROUND: To demonstrate how assessment of life expectancy and loss in expectation of life can be used to address a wide range of research questions of public health interest pertaining to the prognosis of cancer patients. METHODS: We identified 135,092 cases of colon adenocarcinoma diagnosed during 1961-2011 from the population-based Swedish Cancer Register. Flexible parametric survival models for relative survival were used to estimate the life expectancy and the loss in expectation of life. RESULTS: The loss in expectation of life for males aged 55 at diagnosis was 13.5 years (95 % CI 13.2-13.8) in 1965 and 12.8 (12.4-13.3) in 2005. For males aged 85 the corresponding figures were 3.21 (3.15-3.28) and 2.10 (2.04-2.17). The pattern was similar for females, but slightly greater loss in expectation of life. The loss in expectation of life is reduced given survival up to a certain time point post diagnosis. Among patients diagnosed in 2011, 945 life years could potentially be saved if the colon cancer survival among males could be brought to the same level as for females. CONCLUSION: Assessment of loss in expectation of life facilitates the understanding of the impact of cancer, both on individual and population level. Clear improvements in survival among colon cancer patients have led to a gain in life expectancy, partly due to a general increase in survival from all causes.

History

Citation

BMC Cancer, 2015, 15 : 412

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Health Sciences

Version

  • VoR (Version of Record)

Published in

BMC Cancer

Publisher

BioMed Central

eissn

1471-2407

Acceptance date

2015-05-06

Copyright date

2015

Available date

2016-01-28

Publisher version

http://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1427-2

Language

en

Usage metrics

    University of Leicester Publications

    Categories

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC