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Artefactual origin of biphasic cortical spike-LFP correlation.

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journal contribution
posted on 16.11.2016, 10:31 by Michael Okun
Electrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multiple studies, is likely an artefact introduced by high-pass filter of the neural data acquisition system when the actual stLFP has a single trough around the zero lag.

Funding

I would like to thank Sylvia Schroeder and Nicholas Steinmetz for commenting on the manuscript and Kenneth Harris and Matteo Carandini for supporting this work (via Wellcome Trust grants 95668 and 95669).

History

Citation

Journal of Computational Neuroscience, 2016

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/MBSP Non-Medical Departments/Neuroscience, Psychology and Behaviour

Version

VoR (Version of Record)

Published in

Journal of Computational Neuroscience

Publisher

Springer Verlag (Germany)

eissn

1573-6873

Acceptance date

04/09/2016

Copyright date

2016

Available date

16/11/2016

Publisher version

http://link.springer.com/article/10.1007/s10827-016-0625-5

Language

en