Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water
journal contributionposted on 26.10.2015, 13:09 by A. Poma, Antonio Guerreiro, Sarah Caygill, Ewa Moczko, Sergey Piletsky
We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, “ready for use” MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.