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Cancer Drugs Fund requires further reform.

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journal contribution
posted on 16.05.2018, 14:29 by Richard Grieve, Keith Abrams, Karl Claxton, Ben Goldacre, Nicholas James, Jon Nicholl, Mahesh Parmar, Chris Parker, Jasjeet S. Sekhon, Liam Smeeth, David Spiegelhalter, Mark Sculpher
[First paragraph] The reforms to the Cancer Drugs Fund implemented in July were an excellent opportunity to generate evidence on the effectiveness of new cancer drugs.1 Unlike under the previous arrangements, data on patients’ outcomes will have to be collected for all drugs funded by the scheme. However, the reforms’ stated reliance on “real world” (observational) data will not generate reliable evidence of effectiveness. We propose an alternative model, using timely randomised controlled trials within routinely collected data sources, to establish which drugs are relatively effective. The current arrangement encourages early access to drugs, with high prices but uncertain benefits, whereas our proposal will provide high quality evidence for future decisions and therefore larger gains in population health.

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Citation

BMJ, 2016, 354

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Health Sciences

Version

VoR (Version of Record)

Published in

BMJ

Publisher

BMJ Publishing Group

issn

0959-8138

eissn

1756-1833

Copyright date

2016

Available date

16/05/2018

Publisher version

https://www.bmj.com/content/354/bmj.i5090

Language

en

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