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Cardiometabolic risk factor response to a lifestyle intervention: a randomized trial

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journal contribution
posted on 31.07.2015, 09:30 by Deirdre M. Harrington, C. M. Champagne, S. T. Broyles, W. D. Johnson, C. Tudor-Locke, P. T. Katzmarzyk
BACKGROUND: Strategies to increase adherence to national dietary and physical activity (PA) guidelines to improve the health in regions such as the Lower Mississippi Delta (LMD) of the United States are needed. Here we explore the cardiometabolic responses to an education and behavior change intervention among overweight and obese adults that adapted the 2010 Dietary Guidelines (DG), with and without a PA component. METHODS: White and African American overweight and obese adults were randomized to a DG group (n=61) or a DG+PA group (n=60). Both groups received a 12-week dietary education and behavior change intervention, and the DG+PA group also received a PA education and behavior change intervention with a pedometer. Changes in individual risk factors (blood pressure, fasting glucose, triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol) and a continuous cardiometabolic risk score were determined. General linear models compared mean changes between groups, adjusting for covariates. RESULTS: No main effect of intervention group was found in completers (n=99) and those who engaged with ≥80% of the intervention (n=83) for individual risk factors or the continuous risk score. Pooling both groups, those with higher baseline risk factor values realized greater improvements in individual risk factors. CONCLUSIONS: Adapting DG did not produce any cardiometabolic benefits, even with a PA component. Although the sample was ostensibly healthy, they were all overweight to mildly obese (body mass index of 25-34.9 kg/m[superscript: 2]) and participants with higher baseline risk factor values showed more improvements. Adherence to longer-term behavior change may elicit changes in risk profile, so this should be explored.

History

Citation

Metabolic Syndrome and Related Disorders, 2015, 13 (3), pp. 125-131

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine

Version

AM (Accepted Manuscript)

Published in

Metabolic Syndrome and Related Disorders

Publisher

Mary Ann Liebert

issn

1540-4196

eissn

1557-8518

Copyright date

2015

Available date

08/01/2016

Publisher version

http://online.liebertpub.com/doi/10.1089/met.2014.0112

Language

en

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