Cluster of human parechovirus infections as the predominant cause of sepsis in neonates and infants, Leicester, United Kingdom, 8 May to 2 August 2016.
journal contributionposted on 20.08.2019, 14:58 by JW Tang, CW Holmes, FA Elsanousi, A Patel, F Adam, R Speight, S Shenoy, D Bronnert, G Stiefel, P Sundaram, S Pande, A Sridhar, V Kairamkonda, S Bandi
We report an unusually high number of cases (n = 26) of parechovirus infections in the cerebrospinal fluid (CSF) of neonates and infants admitted with sepsis in the United Kingdom during 8 May to 2 August 2016. Although such infections in neonates and infants are well-documented, parechovirus has not been routinely included in many in-house and commercial PCR assays for CSF testing. Clinicians should consider routine parechovirus testing in young children presenting with sepsis.