journal contribution posted on 08.03.2019, 11:49 by K Yeung, F Talbot, GP Howell, A Pulis, DJ Procter
Copper-catalyzed coupling of readily available ketiminoesters, allenes, and a diboron affords densely functionalized quaternary α-amino esters bearing adjacent stereocenters and versatile vinyl boronate motifs. The method utilizes a commercially available copper(I) catalyst, operates at ambient temperature, and features a catalytic allyl cupration of ketiminoesters.
We thank The University of Manchester (President’s Scholarship to K.Y. and Lectureship to A.P.P.), SCI (Scholarship to
K.Y.), AstraZeneca (CASE studentship to F.J.T.T.), EPSRC (Studentship to K.Y. and F.J.T.T. and Established Career
Fellowship to D.J.P.), and Dr. J.M. Suarez, Dr. S. Roland, and Prof. M. Sollogoub ((β-ICyD)CuCl).
CitationACS Catalysis, 2019, 9, 1655−1661
Author affiliation/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry
VersionAM (Accepted Manuscript)
Published inACS Catalysis
PublisherAmerican Chemical Society
NotesThe file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.