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Critique of the "Comment" etitled "Pyrethroid exposure: Not so harmless after all" by Demeneix et al. (2020) published in the lancet diabetes endocrinology

journal contribution
posted on 13.10.2021, 09:44 by Frank A Barile, Sir Colin Berry, Bas Blaauboer, Alan Boobis, Herrmann Bolt, Christopher J Borgert, Wolfgang Dekant, Daniel Dietrich, Jose L Domingo, Gio Batta Gori, Helmut Greim, Jan Hengstler, Sam Kacew, Hans Marquardt, Olavi Pelkonen, Kai Savolainen, Pat Heslop-Harrison, Aristides Tsatsakis, Nico P Vermeulen
Recently, The Lancet published a “Comment” with the title “Pyrethroid exposure: not so harmless after all” (Demeneix et al., 2020). We were surprised to see such a speculative article published by The Lancet. There is no critical evaluation of how the limited number of references (10) cited support – or failed to support - the authors’ unjustified conclusions. The Editor of the Lancet and the manuscript reviewers seem to have made the naive assumption that the mere existence of a putatively hazardous substance in the human body invites restrictive regulation. The article may cause unwarranted public anxiety. Perhaps more importantly, this misguided position fails to satisfy the need for risk assessment which follows hazard identification and is the core of responsible regulatory policy.

The Lancet choose not to publish our criticism of their article. Thus, we are glad to have the opportunity to publish it in Toxicology Letters.

History

Citation

Toxicology Letters Volume 340, 1 April 2021, Pages 1-3

Author affiliation

Department of Genetics and Genome Biology

Version

AM (Accepted Manuscript)

Published in

Toxicology Letters

Volume

340

Pagination

1 - 3

Publisher

Elsevier

issn

0378-4274

eissn

1879-3169

Copyright date

2021

Available date

01/04/2022

Notes

Corrigendum published 24.04.2021: https://doi.org/10.1016/j.toxlet.2021.03.008 The authors regret that the letter inaccurately refers to “the lancet diabetes endocrinology” and “The Lancet” while it should read: “The Lancet Diabetes & Endocrinology”. The correct title of the letter should read: “Critique of the “Comment” entitled: “Pyrethroid exposure: Not so harmless after all” by Demeneix et al. (2020) published in The Lancet Diabetes & Endocrinology”. The authors wish to clarify that the comment was published in The Lancet Diabetes & Endocrinology and not The Lancet. The authors also wish to clarify that The Lancet Diabetes & Endocrinology chose not to publish their criticism of the article because the correspondence content published in The Lancet Diabetes & Endocrinology is only accepted within 8 weeks of publication of the original item.

Spatial coverage

Netherlands

Language

English