Draft Whole-Genome Sequences of Periodontal Pathobionts Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia Contain Phase-Variable Restriction-Modification Systems.pdf (161.28 kB)
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Draft Whole-Genome Sequences of Periodontal Pathobionts Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia Contain Phase-Variable Restriction-Modification Systems.

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posted on 11.01.2018, 09:43 by Richard D. Haigh, Liam A. Crawford, Joseph D. Ralph, Joseph J. Wanford, Sonia R. Vartoukian, Karolin Hijazi, William Wade, Marco R. Oggioni
Periodontal disease comprises mild to severe inflammatory host responses to oral bacteria that can cause destruction of the tooth-supporting tissue. We report genome sequences for 18 clinical isolates of Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia, Gram-negative obligate anaerobes that play a role in the periodontal disease process.

Funding

ACKNOWLEDGMENTS The periodontal strains used were collected during previous studies performed at the University of Cardiff (strains WW414, WW855, and WW2096), University of Bristol (WW2834, WW2842, WW2866, WW2881, WW28585, WW2903, WW2931, WW2952, WW3039, WW3040, and WW3102), King’s College London (WW5019, WW5127, and WW10960), and Queen Mary University of London (WW11663). Illumina sequencing was performed by the NUCLEUS Genomics Core Facility and data analysis used the Spectre2 and Alice2 High Performance Computing Facility at the University of Leicester. This work was in part funded by a grant from the BBSRC (BB/N002903/1) to M.R.O.

History

Citation

Genome Announcements, 2017, 5:e01229-17

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Infection, Immunity and Inflammation

Version

VoR (Version of Record)

Published in

Genome Announcements

Publisher

American Society for Microbiology

issn

2169-8287

Acceptance date

16/10/2017

Copyright date

2017

Available date

11/01/2018

Publisher version

http://genomea.asm.org/content/5/46/e01229-17

Notes

These whole-genome shotgun sequences have been deposited in GenBank and the versions described in this paper are the first versions (see Table 1 for full details).

Language

en

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