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Enantioselective copper catalysed, direct functionalisation of allenes via allyl copper intermediates

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journal contribution
posted on 18.09.2019, 14:32 by Alexander P. Pulis, Kay Yeung, David J. Procter
The direct functionalisation of allenes under copper catalysis enables efficient access to enantioenriched, densely functionalised molecules. In this review we explore the breadth and depth of a versatile reaction manifold, which involves the element-cupration of allenes to generate allyl copper intermediates that are subsequently coupled with diverse arrays of electrophiles.

Funding

We thank the University of Manchester (President's Scholarship to K. Y. and Lectureship to A. P. P.), the SCI (Scholarship to K. Y.), and the EPSRC (Studentships to K. Y. and Established Career Fellowship to D. J. P.). All publication charges for this article have been paid for by the Royal Society of Chemistry

History

Citation

Chemical Science, 2017, 8 (8), pp. 5240-5247

Author affiliation

/Organisation/COLLEGE OF SCIENCE AND ENGINEERING/Department of Chemistry

Version

VoR (Version of Record)

Published in

Chemical Science

Publisher

Royal Society of Chemistry

issn

2041-6520

eissn

2041-6539

Acceptance date

01/06/2017

Copyright date

2017

Available date

18/09/2019

Publisher version

https://pubs.rsc.org/en/content/articlelanding/2017/SC/C7SC01968H#!divAbstract

Language

en

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