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Fungal sensitization and its relationship to mepolizumab response in patients with severe eosinophilic asthma

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journal contribution
posted on 18.06.2021, 09:45 by Andrew Wardlaw, Peter H Howarth, Elliot Israel, Camille Taille, Santiago Quirce, Stephen Mallett, Stewart Bates, Frank C Albers, Namhee Kwon
Letter to the Editor: In asthma, sensitization to fungal, perennial or seasonal allergens increases the risk of uncontrolled symptoms, exacerbations and poor disease outcomes.1 In severe asthma, typically 20%-29% of patients show sensitization to ≥1 fungal allergen, with Aspergillus being one of the most common.2-4 These patients have worse lung function, increased risk of oral corticosteroid use, hospitalization and a greater degree of airflow obstruction than patients non-sensitized to fungal allergens. [opening paragraph]

Funding

GlaxoSmithKline

History

Citation

Clinical & Experimental Allergy, Volume 50, Issue 7, July 2020, pp. 869-872

Author affiliation

Department of Respiratory Sciences, University of Leicester

Version

VoR (Version of Record)

Published in

Clinical and experimental allergy

Volume

50

Issue

7

Pagination

869 - 872

Publisher

WILEY

issn

0954-7894

eissn

1365-2222

Acceptance date

29/05/2020

Copyright date

2020

Available date

18/06/2021

Spatial coverage

England

Language

English

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