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Identification of the remains of King Richard III

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journal contribution
posted on 09.11.2015, 11:01 by Turi E. King, Gloria Gonzalez Fortes, Patricia Balaresque, Mark G. Thomas, David Balding, Pierpaolo Maisano Delser, Rita Neumann, Walther Parson, Michael Knapp, Susan Walsh, Laure Tonasso, John Holt, Manfred Kayser, Jo Appleby, Peter Forster, David Ekserdjian, Michael Hofreiter, Kevin Schürer
In 2012, a skeleton was excavated at the presumed site of the Grey Friars friary in Leicester, the last-known resting place of King Richard III. Archaeological, osteological and radiocarbon dating data were consistent with these being his remains. Here we report DNA analyses of both the skeletal remains and living relatives of Richard III. We find a perfect mitochondrial DNA match between the sequence obtained from the remains and one living relative, and a single-base substitution when compared with a second relative. Y-chromosome haplotypes from male-line relatives and the remains do not match, which could be attributed to a false-paternity event occurring in any of the intervening generations. DNA-predicted hair and eye colour are consistent with Richard's appearance in an early portrait. We calculate likelihood ratios for the non-genetic and genetic data separately, and combined, and conclude that the evidence for the remains being those of Richard III is overwhelming.

History

Citation

Nature Communications, 2014, 5:5631

Author affiliation

/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/MBSP Non-Medical Departments/Department of Genetics

Version

VoR (Version of Record)

Published in

Nature Communications

Publisher

Nature Publishing Group

eissn

2041-1723

Copyright date

2014

Available date

09/11/2015

Publisher version

http://www.nature.com/ncomms/2014/141202/ncomms6631/full/ncomms6631.html#close

Language

en