MECHANISMS IN ENDOCRINOLOGY: Diabetic cardiomyopathy: pathophysiology and potential metabolic interventions state of the art review.pdf (466.9 kB)
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MECHANISMS IN ENDOCRINOLOGY: Diabetic cardiomyopathy: pathophysiology and potential metabolic interventions state of the art review.

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journal contribution
posted on 30.04.2018, 11:05 by Eylem Levelt, Gaurav Gulsin, Stefan Neubauer, Gerry P McCann
Heart failure is a major cause of morbidity and mortality in type 2 diabetes. Type 2 diabetes contributes to the development of heart failure through a variety of mechanisms, including disease-specific myocardial structural, functional and metabolic changes. This review will focus on the contemporary contributions of state of the art non-invasive technologies to our understanding of diabetic cardiomyopathy, including data on cardiac disease phenotype, cardiac energy metabolism and energetic deficiency, ectopic and visceral adiposity, diabetic liver disease, metabolic modulation strategies and cardiovascular outcomes with new classes of glucose-lowering therapies.

History

Citation

European Journal of Endocrinology, 2018, 178 (4), pp. R127-R139

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Cardiovascular Sciences

Version

VoR (Version of Record)

Published in

European Journal of Endocrinology

Publisher

BioScientifica

issn

0804-4643

eissn

1479-683X

Copyright date

2018

Available date

30/04/2018

Publisher version

http://www.eje-online.org/content/178/4/R127

Language

en