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Nonproliferative and Proliferative Lesions of the Gastrointestinal Tract, Pancreas and Salivary Glands of the Rat and Mouse

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journal contribution
posted on 17.05.2016, 13:08 by T. Nolte, P. Brander-Weber, C. Dangler, U. Deschl, M. R. Elwell, Peter Greaves, R. Hailey, M. W. Leach, A. R. Pandiri, A. Rogers, C. C. Shackelford, A. Spencer, T. Tanaka, J. M. Ward
The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) project is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature and diagnostic criteria for nonproliferative and proliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature and diagnostic criteria for classifying lesions in the digestive system including the salivary glands and the exocrine pancreas of laboratory rats and mice. Most lesions are illustrated by color photomicrographs. The standardized nomenclature, the diagnostic criteria, and the photomicrographs are also available electronically on the Internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous and age related lesions as well as lesions induced by exposure to test items. Relevant infectious and parasitic lesions are included as well. A widely accepted and utilized international harmonization of nomenclature and diagnostic criteria for the digestive system will decrease misunderstandings among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.

History

Citation

Journal of Toxicologic Pathology 2016; 29 (1 Suppl): 1S–124S

Version

VoR (Version of Record)

Published in

Journal of Toxicologic Pathology 2016; 29 (1 Suppl): 1S–124S

Publisher

Japenese Society of Toxicological Pathology

issn

0914-9198

eissn

1881-915X

Available date

17/05/2016

Publisher version

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765498/

Notes

PMCID: PMC4765498

Language

en