Novel insights into the mechanisms of mitotic spindle assembly by Nek kinases
journal contributionposted on 06.04.2016, 10:00 by Suzanna L. Prosser, Laura O'Regan, Andrew M. Fry
The mitotic spindle is the apparatus upon which chromosomes are segregated during cell division. We have discovered new roles for two members of the NIMA-Related Kinase (NEK) family in different molecular processes of spindle assembly. Moreover, loss of these proteins leads to segregation errors that drive cancer progression.