Kunutsor2018_Article_Short-termEffectsOfFinnishSaun.pdf (1008.08 kB)
Download file

Short-term effects of Finnish sauna bathing on blood-based markers of cardiovascular function in non-naive sauna users

Download (1008.08 kB)
journal contribution
posted on 06.09.2018, 14:42 by Setor K. Kunutsor, Arja Häkkinen, Francesco Zaccardi, Tanjaniina Laukkanen, Earric Lee, Peter Willeit, Hassan Khan, Jari A. Laukkanen
Emerging evidence suggests that sauna bathing is associated with reduced risk of cardiovascular and all-cause mortality events. However, the biochemical pathways by which sauna bathing might confer its effects on cardiovascular function are not certain. We aimed to study the acute effects of Finnish sauna bathing on various blood-based cardiovascular biomarkers. The study included 102 non-naive sauna users (54% male) with mean age of 51.9 years, who had at least one cardiovascular risk factor. Participants underwent a 30-min single sauna session (mean temperature, 73 °C). Biochemical profiling was conducted before, immediately after sauna and 30-min post-sauna. Overall median N-terminal pro-B-type natriuretic peptide (NT-proBNP) level (n = 20 participants) was 46.0 ng/L before sauna exposure, which increased to 50.5 ng/l immediately after sauna (median change, + 12.00%; p < 0.001) and remained persistent at 30-min post-sauna (median change from pre-sauna to post-30-min sauna, + 13.93%; p < 0.001). The changes were more evident in males compared with females. There were no significant changes in overall levels of high sensitivity C-reactive protein, creatine kinase, high sensitivity troponin I, and creatine kinase-MBm. However, levels of creatine kinase increased in males (median change immediately after sauna, + 2.99%; p = 0.024). Levels of NT-proBNP increased after sauna exposure. The increase in levels of creatine kinase was more evident in males. Long-term interventional studies are warranted to evaluate if these biomarkers are involved in pathways underlying the associations of sauna bathing with cardiovascular outcomes.

History

Citation

Heart and Vessels, 2018, pp. 1-10

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Health Sciences

Version

VoR (Version of Record)

Published in

Heart and Vessels

Publisher

Springer Verlag

issn

0910-8327

eissn

1615-2573

Acceptance date

15/06/2018

Copyright date

2018

Available date

06/09/2018

Publisher version

https://link.springer.com/article/10.1007/s00380-018-1202-9

Language

en

Usage metrics

Categories

Keywords

Licence

Exports