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Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)

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journal contribution
posted on 06.06.2019, 14:13 by W Zingg, BJ Park, J Storr, R Ahmad, C Tarrant, E Castro-Sanchez, E Perencevich, A Widmer, K-H Krause, C Kilpatrick, S Tomczyk, B Allegranzi, D Cardo, D Pittet
Background The high burden of healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) is partially due to excessive antimicrobial use both in human and animal medicine worldwide. How can technology help to overcome challenges in infection prevention and control (IPC) and to prevent HAI and emerging AMR? Methods In June 2017, 42 international experts convened in Geneva, Switzerland to discuss four potential domains of technology in IPC and AMR: 1) role and potential contribution of microbiome research; 2) whole genome sequencing; 3) effectiveness and benefit of antimicrobial environmental surfaces; and 4) future research in hand hygiene. Results Research on the microbiome could expand understanding of antimicrobial use and also the role of probiotics or even faecal transplantation for therapeutic purposes. Whole genome sequencing will provide new insights in modes of transmission of infectious diseases. Although it is a powerful tool for public health epidemiology, some challenges with interpretation and costs still need to be addressed. The effectiveness and cost-effectiveness of antimicrobially coated or treated environmental high-touch surfaces requires further research before they can be recommended for routine use. Hand hygiene implementation can be advanced, where technological enhancement of surveillance, technique and compliance are coupled with reminders for healthcare professionals. Conclusions The four domains of technological innovation contribute to the prevention of HAI and AMR at different levels. Microbiome research may offer innovative concepts for future prevention, whole genome sequencing could detect new modes of transmission and become an additional tool for effective public health epidemiology, antimicrobial surfaces might help to decrease the environment as source of transmission but continue to raise more questions than answers, and technological innovation may have a role in improving surveillance approaches and supporting best practice in hand hygiene.

Funding

The 2017 Geneva IPC-Think Tank was supported by the US Centers for Disease Prevention and Control, and the University of Geneva Hospitals, Switzerland.

History

Citation

Antimicrobial Resistance and Infection Control, 2019, 8:83

Author affiliation

/Organisation/COLLEGE OF LIFE SCIENCES/School of Medicine/Department of Health Sciences

Version

VoR (Version of Record)

Published in

Antimicrobial Resistance and Infection Control

Publisher

BMC (part of Springer Nature)

issn

2047-2994

Acceptance date

13/05/2019

Copyright date

2019

Available date

06/06/2019

Publisher version

https://aricjournal.biomedcentral.com/articles/10.1186/s13756-019-0538-y

Language

en