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Enantoioselective reactions of some optically active phosphines.

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posted on 19.11.2015, 08:45 by G. F. Jay
The enantioselective chlorination of alcohols by the menthyldipheny1-phosphine/carbon tetrachloride reagent previously reported in the literature was investigated and quantified. Further examples were found. A new enantioselective reaction of menthyldipheny1phosphine/carbon tetrachloride was discovered. This was the synthesis of aziridines by ring closure of ? amino alcohols. Other optically active phosphines in conjunction with carbon tetrachloride were found to react in a similar manner to menthy1dipheny1phosphine/carbon tetrachloride with a variety of ? amino alcohols. Menthy1dipheny1phosphine was found to react enantioselectively with a ? amino alcohol in the presence of chlorine.

History

Date of award

01/01/1987

Author affiliation

Chemistry

Awarding institution

University of Leicester

Qualification level

Doctoral

Qualification name

PhD

Language

en

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