U555213.pdf (21.1 MB)
Download file

Gene expression and cleavage arrest in the human embryo.

Download (21.1 MB)
thesis
posted on 19.11.2015, 08:59 by J. K. Artley
In vitro fertilisation and embryo transfer (IVF-ET) is now an accepted part of clinical practice for the treatment of infertility offering live birth rates in the region of 24% per cycle when three embryos are returned to the uterus However analysis of success in terms of the number of established conceptions per embryo returned reveals that only 10.9% of embryos transferred implant. Achieving improved success for IVP-ET, especially following the replacement of a single embryo in order to reduce the risk of multiple pregnancy is undoubtedly dependent on an improved understanding of the mechanisms that lead to embryonic failure.

History

Date of award

01/01/1993

Author affiliation

English

Awarding institution

University of Leicester

Qualification level

Doctoral

Qualification name

MD

Language

en

Usage metrics

Categories

Keywords

Exports