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Lesley M. E. McCowan, John M. D. Thompson, Rennae S. Taylor, Philip N. Baker, Robyn A. North, Lucilla Poston, Claire T. Roberts, Nigel A. B. Simpson, James J. Walker, Jenny Myers, Louise C. Kenny, On behalf of the SCOPE consortium
Prediction of Small for Gestational Age Infants in Healthy Nulliparous Women Using Clinical and Ultrasound Risk Factors Combined with Early Pregnancy Biomarkers
www.plosone.org
www.plosone.org
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(preeclampsia)Tj
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(and/or)Tj
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1 j
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7.4999 0 0 6.6659 514.4314 641.537 cm
BT
/F6 1 Tf
1 TL
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(7)Tj
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q
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11.9999 0 0 11.9999 200.0125 610.8661 cm
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1.0998 0 Td
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0 Tc
3.1521 0 Td
()Tj
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0.9921 0 Td
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1.6158 0 Td
(or)Tj
1.0941 0 Td
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0.83 0.64 0.02 0 k
(23)Tj
0 g
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0.83 0.64 0.02 0 k
7.1999 0 Td
(25)Tj
0 g
(])Tj
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1.5081 0 Td
[()29()4()4()]TJ
2.0919 0 Td
[()13()18()20()11()18()4()]TJ
3.0898 0 Td
[()24()-13()4()2()-19(\n)11()2(\r)10()4()11()]TJ
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[()]TJ
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(1)Tj
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(or)Tj
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(20)Tj
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[()]TJ
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4.6318 0 Td
[()28()11()]TJ
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1.0262 0 Td
(all)Tj
1.1452 0 Td
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(who)Tj
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(did)Tj
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(not)Tj
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(without)Tj
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Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 437.6692 cm
BT
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1 TL
-0.0033 Tc
0 0 Td
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Q
q
1 j
1 J
0 w
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BT
/F6 1 Tf
1 TL
-0.004 Tc
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1.3379 0 Td
(allow)Tj
2.3357 0 Td
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1.389 0 Td
(model)Tj
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(data)Tj
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1.6951 0 Td
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3.702 0 Td
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1.1849 0 Td
(randomly)Tj
4.1272 0 Td
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1.4683 0 Td
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2.0012 0 Td
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3.7587 0 Td
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1.1792 0 Td
(geographical)Tj
5.3007 0 Td
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(rates)Tj
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Q
q
1 j
1 J
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BT
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1 TL
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(and)Tj
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Q
q
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1 J
0 w
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BT
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Q
q
1 j
1 J
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11.9999 0 0 11.9999 200.0125 286.2425 cm
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-0.0033 Tc
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Q
q
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1 J
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BT
/F6 1 Tf
1 TL
-0.004 Tc
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(three)Tj
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(were)Tj
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(angiogenesis)Tj
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(iii\))Tj
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(an)Tj
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(preeclampsia,)Tj
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(26)Tj
0 g
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2.4322 0 Td
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(total)Tj
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(cholesterol,)Tj
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(HDL-)Tj
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(cholesterol,)Tj
4.7791 0 Td
(insulin,)Tj
3.2145 0 Td
(LDL-cholesterol,)Tj
6.9392 0 Td
(human)Tj
3.0784 0 Td
(placental)Tj
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(growth)Tj
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(hormone,)Tj
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6.1001 0 Td
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(material)Tj
-34.0268 -1.2983 Td
(\()Tj
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(S1)Tj
1.508 0 Td
(Appendix)Tj
0 g
4.1725 0 Td
(and)Tj
1.7292 0 Td
(Table)Tj
2.4434 0 Td
(B)Tj
0.7994 0 Td
(in)Tj
0.83 0.64 0.02 0 k
1.0375 0 Td
(S1)Tj
1.1678 0 Td
(Appendix)Tj
0 g
(\).)Tj
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Q
q
1 j
1 J
0 w
11.9999 0 0 11.9999 200.0125 151.9937 cm
BT
/F0 1 Tf
1 TL
-0.0033 Tc
0 0 Td
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4.4504 0 Td
(analysis)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 200.0125 134.9858 cm
BT
/F6 1 Tf
1 TL
-0.004 Tc
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(SAS)Tj
1.8538 0 Td
(\(version)Tj
3.4923 0 Td
(9.3\))Tj
1.7404 0 Td
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2.3641 0 Td
(N.C.)Tj
2.0749 0 Td
(was)Tj
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(used)Tj
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1.3833 0 Td
(statistical)Tj
3.9117 0 Td
(analyses.)Tj
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1.7802 0 Td
(comparison)Tj
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(group)Tj
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(All-)Tj
-35.0359 -1.2982 Td
(SGA)Tj
2.0919 0 Td
(was)Tj
1.7008 0 Td
(Not-SGA,)Tj
4.2122 0 Td
(for)Tj
1.389 0 Td
(`Normotensive-SGA')Tj
8.6003 0 Td
(was)Tj
1.7007 0 Td
(`Not)Tj
1.9843 0 Td
(Normotensive-SGA)Tj
7.9483 0 Td
(')Tj
0.4308 0 Td
(\(all)Tj
1.4854 0 Td
(women)Tj
3.2031 0 Td
(who)Tj
-34.7468 -1.2983 Td
(did)Tj
1.542 0 Td
(not)Tj
1.5704 0 Td
(have)Tj
2.0636 0 Td
(`Normotensive-SGA')Tj
8.6002 0 Td
(including)Tj
4.0422 0 Td
(those)Tj
2.3414 0 Td
(with)Tj
1.9956 0 Td
(`Hypertensive-SGA'\),)Tj
8.7647 0 Td
(and)Tj
1.7291 0 Td
(for)Tj
1.3833 0 Td
(`Hyper-)Tj
-34.0325 -1.3039 Td
(tensive-SGA')Tj
5.4368 0 Td
(the)Tj
1.4683 0 Td
(comparison)Tj
4.9776 0 Td
(group)Tj
2.6079 0 Td
(was)Tj
1.7007 0 Td
(`Not)Tj
1.9843 0 Td
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7.971 0 Td
(\(all)Tj
1.4853 0 Td
(women)Tj
3.2031 0 Td
(who)Tj
1.9389 0 Td
(did)Tj
1.5477 0 Td
(not)Tj
-34.3216 -1.2983 Td
(have)Tj
2.0579 0 Td
(`HypertensiveSGA')Tj
8.7703 0 Td
(including)Tj
4.0422 0 Td
(those)Tj
2.3357 0 Td
(with)Tj
2.0013 0 Td
(`Normotensive-SGA'\).)Tj
9.1672 0 Td
(Comparison)Tj
5.2157 0 Td
(of)Tj
ET
Q
q
1 j
1 J
0 w
576 737.1 m
36 737.1 l
36 737.6 l
576 737.6 l
f*
36 741.2598 107.1496 23.6976 re
W* n
q
107.0929 0 0 23.6409 36 741.3165 cm
q
/I0 Do
Q
Q
Q
q
0 0 612 792 re
W* n
1 j
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